Paul Konerko hit a three-run home run off Justin Germano in the eighth inning to lift the White Sox past the Indians, 6-4, Wednesday afternoon at Progressive Field.
The win completed a three-game sweep of Cleveland, which has lost ninth time in 12 games.
The loss ruined an impressive season debut for Indians right-hander Carlos Carrasco, who allowewd three runs runs over 7 1/3 innings.